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- $Unique_ID{BRK03900}
- $Pretitle{}
- $Title{Keratosis, Seborrheic}
- $Subject{Keratosis, Seborrheic Keratosis Seborrheica Seborrheic Warts Senile
- Warts Verruca Acanthotic Nevus Malignant Melanoma Pigmented Basal Cell
- Carcinoma }
- $Volume{}
- $Log{}
-
- Copyright (C) 1987, 1990 National Organization for Rare Disorders, Inc.
-
- 437:
- Keratosis, Seborrheic
-
- ** IMPORTANT **
- It is possible the main title of the article (Seborrheic Keratosis) is
- not the name you expected. Please check the SYNONYMS listing on the next
- page to find alternate names, disorder subdivisions, and related disorders
- covered by this article.
-
- Synonyms
-
- Keratosis Seborrheica
- Seborrheic Warts
- Senile Warts
- Verruca
- Acanthotic Nevus
-
- Information on the following diseases can be found in the Related
- Disorders section of this report:
-
- Malignant Melanoma
- Pigmented Basal Cell Carcinoma
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources
- section of this report.
-
- Seborrheic Keratosis is a skin disorder usually characterized by
- discolored lesions that appear to be "stuck on" the skin surface. Warts may
- appear and skin is often oily or greasy. These skin lesions are sometimes
- mistaken for cancerous growths and tend to appear predominately during middle
- age. Itching, irritation, inflammations or unsightliness of lesions may
- require surgical removal of affected skin areas.
-
- Symptoms
-
- Symptoms of Seborrheic Keratosis are limited to discolored skin lesions that
- appear to be "stuck on" the skin surface. These patches can appear suddenly,
- vary in size, and they tend to grow slowly. They are round or oval-shaped,
- and are either tan, yellowish, brown or black. They can be widespread over
- the trunk, back, and/or shoulders. Some cases may be limited to a small area
- such as the temples or the cheeks. The skin lesions may also be waxy,
- scaling or crusted. They tend to become darker and larger with age.
-
- Causes
-
- The exact cause of Seborrheic Keratosis is not known although researchers
- believe some forms may be inherited as a dominant trait. (Human traits
- including the classic genetic diseases, are the product of the interaction of
- two genes for that condition, one received from the father and one from the
- mother. In dominant disorders, a single copy of the disease gene (received
- from either the mother or father) will be expressed "dominating" the normal
- gene and resulting in appearance of the disease. The risk of transmitting
- the disorder from affected parent to offspring is 50% for each pregnancy
- regardless of the sex of the resulting child.)
-
- Affected Population
-
- Seborrheic Keratosis predominately affects middle aged individuals, although
- in very rare cases, it can be present at birth.
-
- Related Disorders
-
- Symptoms of the following disorders can be similar to those of Seborrheic
- Keratosis. Comparisons may be useful for a differential diagnosis:
-
- Malignant Melanoma is a type of skin cancer that is characterized by
- rapid growth of cells which form melanin (normal skin pigmentation). These
- melanomas can appear on any part of the body. In early stages, skin lesions
- of various sizes, shapes and colors may resemble those found in Seborrheic
- Keratosis. A skin biopsy may be necessary to confirm the diagnosis. If
- left untreated, abnormal cells may invade various body organs.
-
- Pigmented Basal Cell Carcinoma is characterized by localized, slow
- growing skin nodules which rarely spread to other parts of the body. These
- small, shiny and firm growths are associated with skin or hair follicle
- cells. Ulcerated, crusted lesions, and flat, scar-like plaques with hardened
- skin may also develop.
-
- Therapies: Standard
-
- Since Seborrheic Keratosis is not a form of skin cancer, treatment is not
- essential and removal of lesions is usually performed only to enhance
- comfort and/or cosmetic appearance. Treatment of Seborrheic Keratosis
- consists of removal of the skin lesions by scraping (curettage), sealing off
- blood vessels or destruction of lesions (electrodessication) with local
- anesthetic, shave excision, or freezing with CO2 snow or liquid nitrogen.
- Trichloroacetic acid may be used to eliminate lesions. Dermabrasion removal
- may also be performed. In most cases, scarring is not associated with
- removal of these skin lesions.
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through June
- 1990. Since NORD's resources are limited, it is not possible to keep every
- entry in the Rare Disease Database completely current and accurate. Please
- check with the agencies listed in the Resources section for the most current
- information about this disorder.
-
- Resources
-
- For more information on Seborrheic Keratosis, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- The National Arthritis and Musculoskeletal and Skin Diseases Information
- Clearinghouse
- Box AMS
- Bethesda, MD 20892
- (301) 495-4484
-
- For genetic information, contact:
-
- March of Dimes Birth Defects Foundation
- 1275 Mamaroneck Avenue
- White Plains, NY 10605
- (914) 428-7100
-
- Alliance of Genetic Support Groups
- 35 Wisconsin Circle, Suite 440
- Chevy Chase, MD 20815
- (800) 336-GENE
- (301) 652-5553
-
- References
-
- SEBORRHEIC KERATOSES: A.H. Kettler, et al.; Am Fam Physician (August 1986,
- issue 34(2) ). Pp. 147-152.
-
- DIFFERENTIATING SEBORRHEIC KERATOSIS FROM SKIN NEOPLASM: R.W. Cashmore,
- et al.; Geriatrics (July 1985, issue 40(7)). Pp. 69-71, 74-75.
-
- DERMABRASION FOR THE TREATMENT OF A GIANT SEBORRHEIC KERATOSIS: E
- Pepper; J Dermatol Surg Oncol (June 1985, issue 11(6)). Pp. 646-647.
-
-